Scientific Research
e/MTIC symposium TU/e
RPA Janssen MD PhD visits the Symposium Technology meets Value-Based Health Care. This...
Two new publications
RPA Janssen MD PhD is co-author of 2 new peer reviewed publications this month in Knee...
Keynote lecture KNGF: Up to date treatment ACL injury
Nicky van Melick PT PhD and Rob...
Follow me!
Remain up to date with all the latest knee facts via Facebook, Twitter and other social networks
High systemic gentamycin levels and ototoxicity after implantation of gentamycin beads in a 70-year-old man-a case report
Klaver de PA, Koning J, Janssen RPA, Derijks LJ
Acta Orthopaedica 2009;80(6):734-6
Gentamycin beads are used for muskuloskeletal infections. Gentamycin is released gradually from the beads, and high gentamycin concentrations are achieved only locally. Side effects of gentamycin are rarely to be expected with gentamycin beads since only low amounts of gentamycin are released from the beads, resulting in extremely low serum concentrations of the antibiotic. Only one case of prolonged raised gentamycin serum levels from gentamycin beads has been described to date, but no adverse affects were reported in that case. We present another case with ototoxicity.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823315/?tool=pubmed