Scientific Research

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slijtage: informatie, klachten, diagnose en behandeling. Hockey en voorste kruisband; Kniespecialist RPA Janssen
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e/MTIC symposium TU/e

RPA Janssen MD PhD visits the Symposium Technology meets Value-Based Health Care. This...

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Two new publications

RPA Janssen MD PhD is co-author of 2 new peer reviewed publications this month in Knee...

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Keynote lecture KNGF: Up to date treatment ACL injury

Nicky van Melick PT PhD and Rob...

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Remodelling of human hamstring autografts after anterior cruciate ligament reconstruction

Remodelling of human hamstring autografts after anterior cruciate ligament reconstruction

Janssen RPA, Wijk vder J, Fiedler A, Schmidt T, Sala HAGM, Scheffler SU
Knee Surg Sports Traumatol Arthrosc 2011;19:1299-1306

This is a joint research project between Máxima Medical Center Eindhoven (The Netherlands) and Charité University Hospital Berlin (Germany). Remodelling of human hamstring tendons after anterior cruciate ligament (acl) reconstructions by histological analysis. 67 patients underwent retrieval of biopsies between 6-117 months after acl reconstruction. Hamstring grafts showed typical stages of known remodelling process which was not finished up to 2 years after acl reconstruction. Especially the increasing myofibroblast density, from 12-24 months, allows to reason that the remodelling process in humans is elongated compared to the results from animal experimental studies.

The study has been nominated for the Prof Rik Huiskes Prijs 2013 and has been presented .
The results have been presented at the 14th ESSKA Congress (2010; Oslo, Norway), IMUKA 2010 Congress (2011; Maastricht, The Netherlands), 8th Biennial ISAKOS Congress (2011; Rio de Janeiro, Brazil) and the NOV Annual Congress 2013 (Amsterdam, The Netherlands).


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RPA Janssen, MD PhD 
Orthopaedic Surgeon
Orthopaedic Associates Eindhoven Greater Area
Orthopedic Center Máxima
Máxima Medical Center (MMC)

Visiting adress MMC Eindhoven:
Ds. Th. Fliednerstraat 1
Ingang Zuid
5631 BM  Eindhoven
The Netherlands 
(outpatient clinic and surgery)

Visiting adress MMC Veldhoven:
De Run 4600
5504 DB  Veldhoven
The Netherlands
(Outpatient clinic)

Mail adress:
Postbus 90052
5600 PD  Eindhoven
The Netherlands

Tel. 0031 (0)40 88 88 600
(Call center Orthopedie)

Fax: 0031 (0)40 88 85 938

Orthopaedic Associates Eindhoven Greater Area
Máxima Medical Center
Orthopaedic Center Máxima

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