Knie-artrose

Fietsen verstandig?

Feit

Bij hardlopen wordt de knie belast met 6x uw lichaamsgewicht bij elke stap

Máxima Medisch Centrum

Value-Based Health Care

ESSKA Accredited Teacher

Orthopedie Groot Eindhoven

Goede uitleg is essentieel voor juiste keuze behandeling

Meniscus-scheur

Voorste kruisbandreconstructie

Achterste kruisbandletsel

Zorg op maat

YouTube kanaal dr RPA Janssen

Internationaal wetenschappelijk onderzoek

Kruisbandoperaties knie

RPA Janssen MD PhD

Kruisbandoperaties

Waardegedreven zorg

Last van knie-artrose?

Spreekuur / Policlinique / Outpatient clinic

Nederlandse Vereniging voor Arthroscopie

Máxima Medisch Centrum

Kruisbandoperaties bij kinderen

Veel pijn bij ernstige knie-artrose?

Samen met uw arts gekozen voor een knie-operatie?

Eenzijdige knie-artrose knie en actief leven?

Máxima Medisch Centrum Eindhoven-Veldhoven

Kwaliteit van leven

Samen kiezen voor de beste behandeling

Sporten met plezier

Oplossingen voor de lange termijn

Associate Professor Knee Reconstruction

Fact

Kneecap pain is a regular occurrence in fitness knee rehabilitation

Knee osteoarthritis

Cycling wise?

Fact

When running, the knee is loaded with 6x your body weight with each step

Editor’s Pick Prof Stafano Zaffagnini Journal of Experimental Orthopaedics

Dietvorst, M., Verhagen, S., van der Steen, M. C., van Douveren, F. Q. M. P., & Janssen, R. P. A. (2024). Anterolateral augmentation procedures during anterior cruciate ligament reconstructions in skeletally immature patients: Scoping review of surgical techniques and outcomes.
Journal of Experimental Orthopaedics, 2024:11(1), Article e12012. https://doi.org/10.1002/jeo2.12012
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Publications

Thesis

Knee-Sport-Traumatology

Clinical outcomes of different autografts used for all-epiphyseal, partial epiphyseal or transphyseal anterior cruciate ligament reconstruction in skeletally immature patients – a systematic review

Clinical outcomes of different autografts used for all-epiphyseal, partial epiphyseal or transphyseal anterior cruciate ligament reconstruction in skeletally immature patients – a systematic review

Abstract Background: Different types of grafts can be used for anterior cruciate ligament reconstruction (ACLR). There is little published data regarding skeletally immature patients. The purpose of this systematic review was to assess the clinical outcomes and...

Verhagen S, Dietvorst M, Delvaux EJLG, Steen van der MC, Janssen RPA
BMC Musculoskelet Disord 24, 630 (2023). https://doi.org/10.1186/s12891-023-06749-4
A machine learning approach reveals features related to clinicians’ diagnosis of clinically relevant knee osteoarthritis

A machine learning approach reveals features related to clinicians’ diagnosis of clinically relevant knee osteoarthritis

Abstract Objectives To identify highly-ranked features related to clinicians' diagnosis of clinically relevant knee osteoarthritis (OA). Methods General practitioners (GPs) and secondary care physicians (SPs) were recruited to evaluate 5-10 years follow-up clinical...

Qiuke Wang, Jos Runhaar, Margreet Kloppenburg, Maarten Boers, Johannes W J Bijlsma, Jaume Bacardit, Sita M A Bierma-Zeinstra, Rob P.A. Janssen as member of the CREDO experts group
Rheumatology (Oxford). 2023 Aug 1;62(8):2732-2739 doi: 10.1093/rheumatology/keac707.
A decellularized and sterilized human meniscus allograft for off-the-shelf meniscus replacement

A decellularized and sterilized human meniscus allograft for off-the-shelf meniscus replacement

Abstract PURPOSE: Meniscus tears are one of the most frequent orthopedic knee injuries, which are currently often treated performing meniscectomy. Clinical concerns comprise progressive degeneration of the meniscus tissue, a change in knee biomechanics, and an early...

Spierings, J., Velthuijs, W., Mansoor, A., Bertrand, M. E., Uquillas, J. A., Ito, K., Janssen, R. P. A., & Foolen, J.
Journal of Experimental Orthopaedics. 2022;9(1), [116]
Study protocol ROTATE-trial: anterior cruciate ligament rupture, the influence of a treatment algorithm and shared decision making on clinical outcome- a cluster randomized controlled trial

Study protocol ROTATE-trial: anterior cruciate ligament rupture, the influence of a treatment algorithm and shared decision making on clinical outcome- a cluster randomized controlled trial

Abstract Background: Anterior cruciate ligament (ACL) rupture is a very common knee injury in the sport active population. There is much debate on which treatment (operative or non-operative) is best for the individual patient. In order to give a more personalized...

de Vos, F. H., Meuffels, D. E., de Mul, M., Askari, M., Ista, E., Polinder, S., Waarsing, E., Bierma-Zeinstra, S. M. A., Reijman, M., & Janssen, R. P. A (ROTATE study group)
BMC Musculoskeletal Disorders, 2022;23(1):117. https://doi.org/doi: 10.1186/s12891-021-04867-5
Diagnostic values of history taking, physical examination and KT-1000 arthrometer for suspect anterior cruciate ligament injuries in children and adolescents: a prospective diagnostic study

Diagnostic values of history taking, physical examination and KT-1000 arthrometer for suspect anterior cruciate ligament injuries in children and adolescents: a prospective diagnostic study

Abstract Background: Diagnosing anterior cruciate ligament (ACL) injuries in children and adolescents are more challenging compared to adults. Delayed diagnosis may result in meniscal or chondral injuries. The aim of this study was to deter- mine the diagnostic values...

Martijn Dietvorst, Marieke C. van der Steen, Max Reijman, Rob P.A. Janssen
BMC Musculoskeletal Disorders, 2022;23(710)
Arthroscopic partial meniscectomy versus physical therapy for traumatic meniscal tears in a young study population: a randomised controlled trial

Arthroscopic partial meniscectomy versus physical therapy for traumatic meniscal tears in a young study population: a randomised controlled trial

Abstract OBJECTIVE: To compare outcomes from arthroscopic partial meniscectomy versus physical therapy in young patients with traumatic meniscal tears. METHODS: We conducted a multicentre, open-labelled, randomised controlled trial in patients aged 18-45 years, with a...

Sabine J A van der Graaff, Susanne M Eijgenraam, Duncan E Meuffels, Eline M van Es, Jan A N Verhaar, Dirk Jan Hofstee, Kiem Gie Auw Yang, Julia C A Noorduyn, Ewoud R A van Arkel, Igor C J B van den Brand, Rob P A Janssen, Wai-Yan Liu, Sita M A Bierma-Zeinstra, Max Reijman
British Journal of Sports Medicine. E-pub ahead of print - 8 Jun 2022. http://doi.org/10.1136/bjsports-2021-105059
A tailored intervention does not reduce low value MRI’s and arthroscopies in degenerative knee disease when the secular time trend is taken into account: a difference-in-difference analysis

A tailored intervention does not reduce low value MRI’s and arthroscopies in degenerative knee disease when the secular time trend is taken into account: a difference-in-difference analysis

Abstract Purpose: To evaluate the effectiveness of a tailored intervention to reduce low value MRIs and arthroscopies among patients ≥ 50 years with degenerative knee disease in 13 Dutch orthopaedic centers (intervention group) compared with all other Dutch...

T. Rietbergen, P.J. Marang-van de Mheen, J. de Graaf, R.L. Diercks, R.P.A. Janssen, H.M.J. van der Linden-van der Zwaag, M.E. van den Akker-van Marle, E.W. Steyerberg, R.G.H.H. Nelissen, L. van Bodegom-Vos (Corresponding author), P. Pander, D.J. Hofstee, R.C.I. van Geenen, K.L.M. Koenraadt, J. P.A.H. Onderwater, Y. V. Kleinlugtenbelt, T. Gosens, T.V.S. Klos, P. C. Rijk, B. DijkstraShow lessA.V.C.M. Zeegers, R.A.G. Hoogeslag, M.H.A. Huis in't Veld, A.A. Polak, N.R. Paulino Pereira, T.M.J.S. Vervest, H.C. van der Veen, N. Lopuhaä
Knee Surgery, Sports Traumatology, Arthroscopy, E-pub ahead of print - 7 Apr 2022. https://doi.org/10.1007/s00167-022-06949-w
Diagnosis of early stage knee osteoarthritis based on early clinical course: data from the CHECK cohort

Diagnosis of early stage knee osteoarthritis based on early clinical course: data from the CHECK cohort

Abstract Background: Early diagnosis of knee osteoarthritis (OA) is important in managing this disease, but such an early diagnostic tool is still lacking in clinical practice. The purpose of this study was to develop diagnostic models for early stage knee OA based on...

Wang, Q., Runhaar, J., Kloppenburg, M., Boers, M., Bijlsma, J. W. J., Bierma-Zeinstra, S. M. A., & Janssen, R. P. A. (Credo study group)
Arthritis Research & Therapy, 2021;23(1):217. https://doi.org/10.1186/s13075-021-02598-5
Evaluating Initial Integration of Cell-Based Chondrogenic Constructs in Human Osteochondral Explants

Evaluating Initial Integration of Cell-Based Chondrogenic Constructs in Human Osteochondral Explants

Integration of an implant with the surrounding tissue is a major challenge in cartilage regeneration. It is usually assessed with in vivo animal studies at the end-stage of implant development. To reduce animal experimentation and at the same time increase screening...

Meike W.A. Kleuskens, João F. Crispim, Corrinus C. van Donkelaar (Corresponding author), Rob P.A. Janssen, Keita Ito
Tissue Engineering Part C: Methods.Jan 2022.34-44
Performing a knee arthroscopy among patients with degenerative knee disease: one-third is potentially low value care

Performing a knee arthroscopy among patients with degenerative knee disease: one-third is potentially low value care

Abstract Purpose The purpose of this study was to assess in which proportion of patients with degenerative knee disease aged 50+ in whom a knee arthroscopy is performed, no valid surgical indication is reported in medical records, and to explore pos- sible...

Rietbergen T, Maren-van de Mheen PJ, Diercks RL, Janssen RPA, van der Linder-van der Zwaag HMJ, Nelissen RGHH, Steyerberg EW, van Bodegom-Vos L, for the SMART study group
Knee Surg, Sports Traumatology, Arthroscopy Online June 19, 2021
Spectroscopic Photoacoustic Imaging of Cartilage Damage

Spectroscopic Photoacoustic Imaging of Cartilage Damage

Abstract Objective: Osteoarthritis (OA) is a chronic joint disease characterized by progressive degradation of cartilage. It affects more than 10% of the people aged over 60 years-old worldwide with a rising prevalence due to the increasingly aging population. OA...

Wu M, van Teeffelen BCJ, Ito K, van der Vosse FN, Janssen RPA, van Donkelaar CC, Lopata RGP
Osteoarthritis Cartilage. 2021 Apr 10;S1063-4584(21)00690-7. doi: 10.1016/j.joca.2021.04.001. Online ahead of print
A patient-specific microtissue platform to compare biological properties in vitro with patient outcome for anterior cruciate ligament reconstruction

A patient-specific microtissue platform to compare biological properties in vitro with patient outcome for anterior cruciate ligament reconstruction

After anterior cruciate ligament (ACL) rupture, reconstructive surgery with a hamstring tendon autograft is often performed. Despite overall good results, ACL re-rupture occurs in up to 10% of the patient population, increasing to 30% of the cases for patients aged...

M. van Vijven, J. Kimenai, B. van Groningen, M.C. van der Steen, R.P.A. Janssen, K. Ito, J. Foolen
Orthopaedic Proceedings VOLUME 103-B, ISSUE SUPP_4 / MARCH 2021 (a supplement to the Bone and Joint Journal
Assessment of graft maturity after anterior cruciate ligament reconstruction using autografts:a systematic review of biopsy and MRI studies

Assessment of graft maturity after anterior cruciate ligament reconstruction using autografts:a systematic review of biopsy and MRI studies

The purpose of this investigation was to evaluate systematically the literature concerning biopsy, MRI signal to noise quotient (SNQ) and clinical outcomes in graft-maturity assessment after autograft anterior cruciate ligament reconstruction (ACLR) and their possible...

B. van Groningen, M. C. van der Steen, D. M. Janssen, L. W. van Rhijn, T. van der Linden, R. P. A. Janssen
Orthopaedic Proceedings VOLUME 103-B, ISSUE SUPP_4 / MARCH 2021 (a supplement to the Bone and Joint Journal
Diagnostic criteria for early hip osteoarthritis; first steps, based on the CHECK study

Diagnostic criteria for early hip osteoarthritis; first steps, based on the CHECK study

Abstract Objectives: Although there is a general focus on early diagnosis and treatment of hip osteoarthritis, there are no validated diagnostic criteria for early-stage hip OA. The current study aimed to take the first steps in developing diagnostic criteria for...

Runhaar J, Özbulut Ö, Kloppenburg M, Boers M, Bijlsma JWJ, Bierma-Zeinstra SMA; CREDO expert group
Rheumatology (Oxford). 2021 Feb 12:keab111. doi: 10.1093/rheumatology/keab111. Online ahead of print
The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort

The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort

Abstract: Objective: The purpose of this study was to evaluate the added value of radiographs for diagnosing knee osteoarthritis (KOA) by general practitioners (GPs) and secondary care physicians (SPs). Methods: Seventeen GPs and nineteen SPs were recruited to...

Qiuke Wang, Jos Runhaar, Margreet Kloppenburg, Maarten Boers, Johannes W. J. Bijlsma, Sita M. A. Bierma-Zeinstra and The CREDO Expert Group
J. Clin. Med. 2020;9:3374; doi:10.3390/jcm9103374
Can sodium MRI be used as a method for mapping of cartilage stiffness?

Can sodium MRI be used as a method for mapping of cartilage stiffness?

Abstract Objective Sodium concentration is responsible for (at least part of) the stiffness of articular cartilage due to the osmotic pressure it generates. Therefore, we hypothesized that we could use sodium MRI to approximate the stiffness of cartilage to assess...

Brinkhof, S., Froeling, M., Janssen, R.P.A., Ito K., Klomp D.W.J.
Magn Reson Mater Phy (2020). https://doi.org/10.1007/s10334-020-00893-x
Rationale and design of the PaTIO study: PhysiotherApeutic Treat-to-target Intervention after Orthopaedic surgery

Rationale and design of the PaTIO study: PhysiotherApeutic Treat-to-target Intervention after Orthopaedic surgery

Abstract Background: Physiotherapy is a proven effective treatment strategy after total knee and hip arthroplasty (TKA/THA), however there is considerable practice variation regarding its timing, content and duration. This study aims to compare the (cost-)...

Groot L, Gademan MGJ, Peter WF, van den Hout WB, Verburg H, Vliet Vlieland TPM, Reijman M; PaTIO study group
BMC Musculoskelet Disord. 2020 Aug 14;21(1):544
Development of a Personalized m/eHealth Algorithm for the Resumption of Activities of Daily Life including Work and Sport after Total and Unicompartmental Knee Arthroplasty: a Multidisciplinary Delphi Study

Development of a Personalized m/eHealth Algorithm for the Resumption of Activities of Daily Life including Work and Sport after Total and Unicompartmental Knee Arthroplasty: a Multidisciplinary Delphi Study

Straat AC, Coenen P, Denise J.M. Smit, Gerben Hulsegge, Esther V.A. Bouwsma, Judith A.F. Huirne, Rutger C. van Geenen, Rob P.A. Janssen, Tim A.E.J. Boymans, Gino M.M.J. Kerkhoffs, Johannes R. Anema, P. Paul F.M. Kuijer
International Journal of Environmental Research and Public Health (accepted July 6, 2020)
An ex vivo human osteochondral culture model

An ex vivo human osteochondral culture model

Abstract To reduce animal experimentation and to overcome translational issues in cartilage tissue engineering, there is a need to develop an ex vivo human tissue-based approach. This study aims to demonstrate that a human osteochondral explant at different...

Kleuskens MWA, Donkelaar van CC, Kock LM, Janssen RPA, Ito K
J Orthop Res. 2021 Apr;39(4):871-879
Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome: a diagnostic in vitro tissue remodeling platform

Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome: a diagnostic in vitro tissue remodeling platform

Abstract Purpose: Upon anterior cruciate ligament (ACL) rupture, reconstruction is often required, with the hamstring tendon autograft as the most widely used treatment. Post-operative autograft remodeling enhances the risk of graft rupture, which occurs in up to...

Vijven van M, Groningen van B, Kimenai J, Steen van der MC, Doeselaar van M, Janssen RPA, Ito K, Foolen J
J Exp Orthop. 2020;7(1):48-2
Development of Preoperative Prediction Models for Pain and Functional Outcome After Total Knee Arthroplasty Using The Dutch Arthroplasty Register Data

Development of Preoperative Prediction Models for Pain and Functional Outcome After Total Knee Arthroplasty Using The Dutch Arthroplasty Register Data

Abstract BACKGROUND:  One of the main determinants of treatment satisfaction after total knee arthroplasty (TKA) is the fulfillment of preoperative expectations. For optimal expectation management, it is useful to accurately predict the treatment result. Multiple...

Tolk JJ, Waarsing JEH, Janssen RPA, van Steenbergen LN, Bierma-Zeinstra SMA, Reijman M
J Arthroplasty. 2019 Oct 18. pii: S0883-5403(19)30944-1. doi: 10.1016/j.arth.2019.10.010. [Epub ahead of print]
Current State of Care for Pediatric ACL Ruptures in the Netherlands: A Survey

Current State of Care for Pediatric ACL Ruptures in the Netherlands: A Survey

Abstract The management of anterior cruciate ligament (ACL) injuries in the skeletally immature patient is an area of controversy. The purpose of this survey is to inventory the current state of care for pediatric ACL injuries in the Netherlands. This survey was...

Dietvorst M, Reijman M, van Zutven R, van den Bekerom MPJ, Meuffels DE, Somford MP, Janssen RPA
J Knee Surg 2021; 34(05): 520-525. doi: 10.1055/s-0039-1697626
Preferences and beliefs of Dutch orthopaedic surgeons and patients reduce the implementation of “Choosing Wisely” recommendations in degenerative knee disease

Preferences and beliefs of Dutch orthopaedic surgeons and patients reduce the implementation of “Choosing Wisely” recommendations in degenerative knee disease

Abstract PURPOSE:  The purpose of this study was to assess which factors were associated with the implementation of "Choosing Wisely" recommendations to refrain from routine MRI and arthroscopy use in degenerative knee disease. METHODS: ...

Rietbergen T, Diercks RL, Anker-van der Wel I, van den Akker-van Marle ME, Lopuhaä N, Janssen RPA, van der Linden-van der Zwaag HMJ, Nelissen RGHH, Marang-van de Mheen PJ, van Bodegom-Vos L
Knee Surg Sports Traumatol Arthrosc. 2019 Sep 25. doi: 10.1007/s00167-019-05708-8. [Epub ahead of print] PMID: 31555844
Outcome expectations of total knee arthroplasty patients: the influence of demographic factors, pain, personality traits, physical and psychological status

Outcome expectations of total knee arthroplasty patients: the influence of demographic factors, pain, personality traits, physical and psychological status

Abstract Unfulfilled preoperative expectations have a strong influence on the outcome after total knee arthroplasty (TKA). More insight into determinants of the level of expectations is useful in identifying patients at risk for having expectations of the treatment...

Tolk JJ, Janssen RPA, Runhaar J, Steen van der MC, Bierma-Zeinstra SMA, Reijman M
J Knee Surg. 2019 Jul 4. doi: 10.1055/s-0039-1692632. [Epub ahead of print] PMID: 31272124
Pedi-IKDC or KOOS-Child: which questionnaire should be used in children with knee disorders?

Pedi-IKDC or KOOS-Child: which questionnaire should be used in children with knee disorders?

Abstract BACKGROUND:  The Pedi International Knee Documentation Committee (IKDC) and Knee Injury and Osteoarthritis Outcome Score (KOOS) child are validated questionnaires for children with knee disorders. The aim of this study was to translate these...

van der Velden CA, van der Steen MC, Leenders J, van Douveren FQMP, Janssen RPA, Reijman M
BMC Musculoskelet Disord. 2019 May 22;20(1):240. doi: 10.1186/s12891-019-2600-6
Measurement properties of the OARSI core set of performance-based measures for hip osteoarthritis. A prospective cohort study on reliability, construct validity and responsiveness in 90 hip osteoarthritis patients.

Measurement properties of the OARSI core set of performance-based measures for hip osteoarthritis. A prospective cohort study on reliability, construct validity and responsiveness in 90 hip osteoarthritis patients.

Abstract Background and purpose - Improvement of physical function is one of the main treatment goals in severe hip osteoarthritis (OA) patients. The Osteoarthritis Research Society International (OARSI) has identified a core set of performance-based tests to assess...

Tolk JJ, Janssen RPA, Prinsen C, van der Steen MC, Sita Bierma-Zeinstra S, Reijman M
Acta Orthop. 2019 Feb;90(1):15-20
The EKSPECT study: the influence of Expectation modification in Knee arthroplasty on Satisfaction of PatiEnts: study protocol for a randomized Controlled Trial

The EKSPECT study: the influence of Expectation modification in Knee arthroplasty on Satisfaction of PatiEnts: study protocol for a randomized Controlled Trial

Abstract Background: One out of five patients is unsatisfied to some extent after total knee arthroplasty (TKA). Unmet expectations are the main driver of post-operative dissatisfaction. Improved pre-operative education on realistic expectations for long-term...

Tolk JJ, Janssen RPA, Haanstra TM, Bierma-Zeinstra SMA, Reijman M
Trials. 2018 Aug 14;19(1):437. doi: 10.1186/s13063-018-2821-2
The OARSI core set of performance-based measures for knee osteoarthritis is reliable but not valid and responsive

The OARSI core set of performance-based measures for knee osteoarthritis is reliable but not valid and responsive

Abstract  Purpose The Osteoarthritis Research Society International has identi ed a core set of performance-based tests of physi- cal function for use in people with knee osteoarthritis (OA). The core set consists of the 30-second chair stand test (30-s...

Tolk JJ, Janssen RPA, Prinsen CAC, Latijnhouwers DAJM, van der Steen MC, Bierma-Zeinstra SMA, Reijman M.
Knee Surg Sports Traumatol Arthrosc. 2019 Sep;27(9):2898-2909
Knee simulator for IKDC testing

Knee simulator for IKDC testing

Voorn S, Vrande vd H, Cock de B, Brand vden J, Bender T, Cuijpers J, Eijnde vden M, Steen van der M, Reijman M, Janssen RPA
FysioPraxis 2017;4:20-21
Validation of Simendo Knee Arthroscopy Virtual Reality Simulator

Validation of Simendo Knee Arthroscopy Virtual Reality Simulator

Abstract PURPOSE:  To determine the face and construct validity as well as educational value and user-friendliness of the Simendo knee arthroscopy virtual reality simulator. METHODS:  Sixty participants were recruited and equally divided into novices (0...

Heijden vd L, Janssen RPA, Steen der M, Reijman M, Tuijthof G
Arthroscopy. 2019 Aug;35(8):2385-2390
Total knee arthroplasty, what to expect? A survey of the members of the Dutch Knee Society on long-term recovery after total knee arthroplasty

Total knee arthroplasty, what to expect? A survey of the members of the Dutch Knee Society on long-term recovery after total knee arthroplasty

Abstract Introduction The rate of satisfaction after total knee arthroplasty (TKA) is consistently reported around 80%, leaving 1 in 5 patients unsatisfied to some extent. Fulfillment of expectations is reported as the strongest predictor of treatment satisfaction. In...

Tolk JJ, van der Steen MC, Janssen RPA, Reijman M.
J Knee Surg. 2017 Jul;30(6):612-616. doi: 10.1055/s-0036-1593868. Epub 2016 Nov 23.
The Pellegrini-Stieda lesion of the knee: an anatomical and radiological review

The Pellegrini-Stieda lesion of the knee: an anatomical and radiological review

The Pellegrini-Stieda lesion is a calcification on the medial side of the knee. The origin of this tissue is controversial. The purpose of our study is to investigate the origin of the Pellegrini-Stieda lesion using conventional radiography as to recreate the...

Somford MP, Janssen RPA, Meijer D, Roeling TAP, Brown C Jr, Eygendaal D
J Knee Surg. 2019 Jul;32(7):637-641
Anterior cruciate ligament reconstruction with hamstring tendon autograft and accelerated brace-free rehabilitation: a systematic review of clinical outcomes

Anterior cruciate ligament reconstruction with hamstring tendon autograft and accelerated brace-free rehabilitation: a systematic review of clinical outcomes

ABSTRACT OBJECTIVE: To investigate the clinical outcomes after hamstring tendon autograft ACL reconstruction with accelerated, brace-free rehabilitation. DESIGN: Systematic review according to PRISMA guidelines. DATA SOURCES: Embase, Medline Ovid, Web...

Janssen RPA, Melick v N, Mourik v JBA, Reijman M, Rhijn v LW
BMJ Open Sport Exerc Med. 2018 Apr 9;4(1):e000301. doi: 10.1136/bmjsem-2017-000301. eCollection 2018
The importance of gait analysis and gait training in knee osteoarthritis

The importance of gait analysis and gait training in knee osteoarthritis

This article describes the role of gait analysis and gait training in the treatment of patients with osteoarthritis based on international guidelines. It is the first piolt study of PhD students J. Tolk and F. Brooymans on gait in osteoarthritis. 

Brooymans FAM, Tolk JJ, Janssen RPA
Physios (2014) 2:38-45
Femoral mechanical-anatomical angle measurements: analog vs. digital

Femoral mechanical-anatomical angle measurements: analog vs. digital

Preoperative planning in total knee arthroplasty with intramedullary guiding systems requires the measurement of the femoral mechanical–anatomical angle (FMAA) for optimal alignment correction. The main goal of this study was to assess the agreement between two...

Groningen van B, Teuling den JWAM, Houterman S, Janssen RPA
J Knee Surg. 2015 Aug;28(4):315-9
Evidence-based clinical practice update: practice guidelines for anterior cruciate ligament rehabilitation based on a systematic review and multidisciplinary consensus

Evidence-based clinical practice update: practice guidelines for anterior cruciate ligament rehabilitation based on a systematic review and multidisciplinary consensus

In 2012, the National Anterior Cruciate Ligament Committee was founded. RPA Janssen M.D., represented the Dutch Orthopaedic Society (NOV) in this committee. Other participating partners were the Dutch Arthroscopy Society (Nederlandse Vereniging voor...

Engelen-van Melick N. et al. (m.m.v. Janssen RPA)
Br J Sports Med 2016;50(24):1506-1515
Anterior cruciate ligament and knee osteoarthritis

Anterior cruciate ligament and knee osteoarthritis

The journal Physios has invited RPA Janssen to write a review article on the subject of anterior cruciate ligament and knee osteoarthritis. Physios is an independent journal with e-learning credits. The article is only available in Dutch.

Janssen RPA
Physios 2011;3(1):23-30
Anterior cruciate ligament regeneration in an 8-year-old patient

Anterior cruciate ligament regeneration in an 8-year-old patient

An 8 year old boy ruptures his anterior cruciate ligament in sports. MRI demonstrates the lesion. He is treated conservatively with a brace. At the age of 14, MRI shows an anatomic healing of the anterior cruciate ligament. He has no more subjective nor objective...

Arts SJ, Polak MPJ, Janssen RPA
J Knee Surg Rep 2015;00:1-4
Computer navigated versus conventional total knee arthroplasty

Computer navigated versus conventional total knee arthroplasty

The study has been awarded Best Poster Award MMC 2011 (see Archives: March 4th, 2011). Out of a consecutive series, 50 conventional TKA were compared with 50 computer assisted TKA.. Except for the use of CAS, all peri- and postoperative interventions were comparable....

Tolk J, Koot HWJ, Janssen RPA
J Knee Surg 2012; 25(04): 347-352
Evidence bases Guideline Acute Knee Injury

Evidence bases Guideline Acute Knee Injury

Development of a new evidence-based clinical practice guidelines for treatment of "Acute Knee Injury". The latest insights and scientific evidence is provided by leading knee specialists and physiotherapists in the Netherlands. 

Brooymans FAM, Lenssen AF, Engelen-van Melick N, Knoop J, Rondhuis G, Neeleman-vder Steen CWM, Tak IJR, Hullegie W, Hendriks HJM, Janssen RPA
KNGF 2015
Leg alignment and tibial slope after minimal invasive total knee arthroplasty:  a prospective randomized radiological study of intramedullary versus extramedullary tibial instrumentation

Leg alignment and tibial slope after minimal invasive total knee arthroplasty: a prospective randomized radiological study of intramedullary versus extramedullary tibial instrumentation

Analysis of long leg alignment as well as tibial slope after minimal invasive total knee arthroplasty (MIS-TKA) comparing intra- and extramedullary minimal invasive surgery (MIS) tibia instrumentation (Genesis II, Smith & Nephew, Memphis, USA). A prospective...

Kroon de KE, Houterman S, Janssen RPA
The Knee 2012;19:270–274
Remodelling of human hamstring autografts after anterior cruciate ligament reconstruction

Remodelling of human hamstring autografts after anterior cruciate ligament reconstruction

This is a joint research project between Máxima Medical Center Eindhoven (The Netherlands) and Charité University Hospital Berlin (Germany). Remodelling of human hamstring tendons after anterior cruciate ligament (acl) reconstructions by histological analysis. 67...

Janssen RPA, Wijk vder J, Fiedler A, Schmidt T, Sala HAGM, Scheffler SU
Knee Surg Sports Traumatol Arthrosc 2011;19:1299-1306
Regeneration of hamstring tendons after anterior cruciate ligament reconstruction

Regeneration of hamstring tendons after anterior cruciate ligament reconstruction

Prospective analysis of regeneration of gracilis and semitendinosis tendons after anterior cruciate ligament reconstruction. MRI is performed préoperatively and at 2 weeks, 6 and 12 months postsurgery. The gracilis tendon regenerated in all 22 patients. The...

Janssen RPA, Velden vder MJF, Pasmans HLM, Sala HAGM
Knee Surg Sports Traumatol Arthrosc. 2013; 21(4): 898-905
Anterior cruciate ligament reconstruction with hamstring tendons and accelerated rehabilitation: a 10-year prospective study on clinical results, knee osteoarthritis and its predictors

Anterior cruciate ligament reconstruction with hamstring tendons and accelerated rehabilitation: a 10-year prospective study on clinical results, knee osteoarthritis and its predictors

Purpose: Analysis of long-term clinical and radiological outcome after anterior cruciate ligament (ACL) reconstruction with special attention to knee osteoarthritis and its predictors. Methods: A prospective, consecutive case series of 100 patients. Arthroscopic...

Janssen RPA, Du Mée AWF, Valkenburg v J, Sala HAGM, Tseng CM
Knee Surg Sports Traumatol Arthrosc. 2013;21-9:1977-1988
Advanced Trauma Life Support-Dutch update 2008

Advanced Trauma Life Support-Dutch update 2008

A tragic airplane crash in 1976 has led to the development of the Advanced Trauma Life Support (ATLS): the current golden standard for the treatment of trauma patients in the acute phase. The founding father of the ATLS, orthopaedic surgeon James K. Styner, has...

Janssen RPA
Nederlands Tijdschrift voor Orthopedie 2008;15(1):19-23
An uncommon ankle sprain

An uncommon ankle sprain

Objective: Ankle sprain is the most frequently occurring acute injury in tennis, accounting for 20–25% of all injuries. In the current paper, we assess the cause of ankle sprain and suggest possibilities to be considered during diagnosis. Methods: We assessed a...

Zoest van WJ, Janssen RPA, Tseng CM
Br J Sports Med 2007;41(11):849-50
Fatal pulmonary embolism after anterior cruciate ligament reconstruction

Fatal pulmonary embolism after anterior cruciate ligament reconstruction

We report a case of fatal pulmonary embolus in a consecutive series of 625 anterior cruciate ligament reconstructions. An analysis of the predisposing factors is presented as well as a literature review of thromboprophylaxis in anterior cruciate ligament...

Janssen RPA, Sala HAGM
Am J Sports Med 2007;35(6):1000-2
Isolated dorsal dislocation of the radial head: a rare phenomenon

Isolated dorsal dislocation of the radial head: a rare phenomenon

Radial head dislocations usually occur in combination with ulna fractures (Monteggia fracture). Dislocation of the radial head is to anterior, lateral or posterior. However, dislocations may be isolated lesions; usually in children betwen 2-7 years of age with an...

Rahusen FThG, Vellema JHBF, Janssen RPA, Scheltinga MRM, Eygendaal D
Ned Tijdschr Traum 2005;13:138-41
Resection of the radial head after Mason type-III fractures of the elbow

Resection of the radial head after Mason type-III fractures of the elbow

We reviewed 21 patients with Mason type-III fractures of the radial head treated by resection, evaluating the results at 16-30 years by a standard questionnaire and clinical and radiological examination of the elbow and wrist. Seventeen patients had an excellent...

Janssen RPA, Vegter J
J Bone Joint Surg [Br] 1998;80-B:231-3
Advanced Trauma Life Support (ATLS): obligatory for internal medicine doctors?

Advanced Trauma Life Support (ATLS): obligatory for internal medicine doctors?

Immobilisation of the cervical spine is mandatory in the adequate primary survey of a trauma patient. This principle is part of the Advanced Trauma Life Support (ATLS) program. The ATLS course is part of the training of surgical and orthopedic residency programs. We...

Janssen RPA, Mourik van JBA
Medisch Journaal 2000;3:131-2
Monteggia fracture or transolecranon dislocation-fracture?

Monteggia fracture or transolecranon dislocation-fracture?

Ulna fractures with dislocation of the radial head are rare injuries. They constutute less than 5% of all fractures of the upper extremity. We describe a case with an ulnar fracture, dislocation of the radial head and simultaneous fracture of the olecranon. The trauma...

Janssen RPA, Sala HAGM, Mourik van JBA
Ned Tijdschr Traum 2000;6:161-4

Books

Pediatric knee injuries

Pediatric knee injuries

Janssen RPA, Mourik JBA
Kramer WLM, Bessems JHJM, Besselaar AT, Edwards M, e.a. Kindertraumachirurgie. Houten, Springer Nature-Bohn, Stafleu, Van Loghum, 2019, 2e herziene druk. ISBN 978 90 368 1869 8. NUR 871.
The new warming-up

The new warming-up

RPA Janssen, MD has contributed to the new book by T. Kamminga: The new warming-up. (Dutch).

T. Kamminga (m.m.w. RPA Janssen)
Tirion Sport, Utrecht, 2011
Trauma Evaluation And Management

Trauma Evaluation And Management

TEAM (Trauma Evaluation And Management) introduces the concepts of trauma assessment and management to medical students during their clinical years. The core content is adapted from the College's successful program, Advanced Trauma Life Support® (ATLS) course....

Janssen RPA, Henny W
In TEAM: Trauma Evaluation And Management. 3rd Edition, 2010
Vascular complications after anterior cruciate ligament reconstruction

Vascular complications after anterior cruciate ligament reconstruction

Vascular complications after anterior cruciate ligament (ACL) reconstructions cause serious morbidity and potential mortality. Fortunately, their incidence is low. Only a few peer-reviewed case reports provide information and even a specific review article on...

Janssen RPA
In Prodromos CC, ed. The Anterior Cruciate Ligament; Reconstruction and Basic Science. Copyright 2008 by Saunders an imprint of Elsevier Inc. Chapter 77:592-7

Other Medical Science

Tweets and tags from dr. Twitter

Tweets and tags from dr. Twitter

Article on surgery and sopcial media. Surgeons experienced in professional use of social media have been interviewed. RPA Janssen, M.D. has shared his experiences in the do and dont's on Twitter, Facebook and LinkIn. 

Talsma K (m.m.v. Janssen RPA, Nieboer B., Boermeester M)
Ned Tijdschr v Heelk 2013;22(3):19-21
Fiber-rich bran therapy: adequate laxative for patients with diverticulosis?

Fiber-rich bran therapy: adequate laxative for patients with diverticulosis?

Fiber-rich therapy with brans has been decribed as succesful by almost all authors in the literature. Very few complications have been decribed for this widespread therapy in use since the 1970's. The complication "bran-plug obstruction" is only mentionned in 6...

Janssen RPA, Muris JWM
Vademecum 1993 11(52):28 december
Methemoglobinemia after sentinel-node procedure?

Methemoglobinemia after sentinel-node procedure?

The sentinel node-procedure is now a valid treatment of breast cancer. The clinical application has been tested in multiple medical centers. The purpose of the procedure is to detect the presence of tumor tissue in the sentinel lymph-node as sign of axillary...

Janssen RPA, Berlo van CLH
Ned Tijdschr Heelkd 1999;8:195-6,206

Congress / Courses (Faculty-Lectures-Posters)

Photoacoustic imaging of cartilage damage

Photoacoustic imaging of cartilage damage

Min Wu, B.C.J. van Teeffelen, Keita Ito, Frans N. van de Vosse, Rob P.A. Janssen, C.C. (René) van Donkelaar, Richard G.P. Lopata
21st ESSKA Congress - Milan, Italy. May 8-10, 2024 (poster)
Meet The Residency Program Director

Meet The Residency Program Director

Prof Janssen MD PhD is invited as speaker on residency programs at the 9th National Master Medicine Congress on March 10, 2024.

RPA Janssen
9e Nationaal Coassistenten Congres, March 8-10, 2024. Egmond aan Zee, The Netherlands
Pediatric ACL injuries

Pediatric ACL injuries

RPA Janssen
Cursus Voorste Kruisbandrevalidatie. SOMT University of Physiotherapy. March 20, 2024. Amersfoort. (Keynote)
Remodeling of ACL grafts

Remodeling of ACL grafts

RPA Janssen
Cursus Voorste Kruisbandrevalidatie. SOMT University of Physiotherapy. March 20, 2024. Amersfoort. (Keynote)
Keynote speaker Master Class NVA

Keynote speaker Master Class NVA

Prof RPA Janssen MD PhD is invited as keynote speaker at the annual Master Class 2023 of the Dutch Arthroscopy Society. He will present a lecture on pediatric ACL injuries. December 8, 2023. Utrecht, The Netherlands

Poster presentation TUe/Maxima MC research group

Poster presentation TUe/Maxima MC research group

A new scientific research project has been accepted as poster presentation at the RegMed XB 1st Annual Conference 2023. Florencia Abinzano, Jeske C.A. Feenstra, Rob P.A. Janssen, Keita Ito. Large-scale cartilage organoid fabrication based on articular cartilage...

Pediatric ACL injuries

Pediatric ACL injuries

RPA Janssen
Cursus Voorste Kruisbandrevalidatie. SOMT University of Physiotherapy (18-01-2023, Amersfoort, The Netherlands)
Remodelling of ACL grafts

Remodelling of ACL grafts

RPA Janssen
Cursus Voorste Kruisbandrevalidatie. SOMT University of Physiotherapy (18-01-2023, Amersfoort, The Netherlands)
ACL reconstruction

ACL reconstruction

RPA Janssen
Cursus Voorste Kruisbandrevalidatie. SOMT University of Physiotherapy (18 januari 2023., Amersfoort, The Netherlands)
Keynote lecture knee injuries

Keynote lecture knee injuries

Prof Janssen MD PhD will present a keynote lecture on the multidisciplinary treatment of acute knee injuries together with N van Melick PT, PhD. They are invited by the Royal National Physiotherapy Society (KNGF). venue KNGF Hoofdkantoor, Amersfoort (Dec 21, 2022)...

Anterolateral augmentation procedures during anterior cruciate ligament reconstructions in skeletally immature patients – scoping review of surgical techniques and outcomes

Anterolateral augmentation procedures during anterior cruciate ligament reconstructions in skeletally immature patients – scoping review of surgical techniques and outcomes

Abstract: Introduction and Objectives: Graft failure rates after anterior cruciate ligament (ACL) reconstruction in children and adolescents are higher compared to adults. Studies have highlighted young age, hyperlaxity and rotatory instability as risk factors for...

Martijn Dietvorst, Stephanie Verhagen, Marieke van der Steen, Florens QMP van Douveren, Rob PA Janssen
41st EPOS Annual Meeting European Pediatric Orthopaedic Society (March 29-April 1, 2023. Krakow, Poland)
Keynote lecture ACL and concomitant injuries

Keynote lecture ACL and concomitant injuries

Prof RPA Janssen MD PhD is invited for a keynote lecture at Post Master Course Knee on November 17, 2022. Title of the lecture is ACL and concomitant knjuiresd of the knee (EIndhoven, The Netherlands).

Top-notch decisions in knee surgery

Top-notch decisions in knee surgery

Link to poster

van der Lande A, Uquillas JA, Janssen RPA, Foolen J, de Boer J
ICMS Annual Symposium 2021. Eindhoven, The Netherlands (March 25, 2021)
ACL Anatomy: what’s new?

ACL Anatomy: what’s new?

Janssen RPA
29th Annual A&A International Advanced Arthroscopy Knee Course (July 3-5, 2018. Utrecht, The Netherlands)
PCL reconstruction

PCL reconstruction

Janssen RPA, MD PhD
Arthroscopy & Arthroplasty Advanced Instructional Course of Arthroscopy on the Knee 2016
PCL Reconstruction

PCL Reconstruction

Janssen RPA
Arthroscopy & Arthroplasty Advanced Knee Course 2015 (July 7-9. Utrecht, the Netherlands)
Anatomic ACL Reconstruction

Anatomic ACL Reconstruction

Janssen RPA
1st Deconstruction to Reconstruction Advanced Knee Instructional Course (York, UK: May 14-15, 2015)
Cruciate ligament injuries & Sport: update 2014

Cruciate ligament injuries & Sport: update 2014

In 2014, the Sports Medicine Center of Excellence has been inaugurated. RPA Janssen is partner in this Center as representative of the Orthopaedic Associates Eindhoven Greater Area & Maxima Medical Center Eindhoven-Veldhoven, The Netherlands. ...

Janssen RPA
Graft remodeling: animal versus human

Graft remodeling: animal versus human

RPA Janssen presented the lecture ACL Graft remodeling: animal versus human at the Unconventional ACL Meeting....The Sequel (Antwerp, Belgium. December 13, 2013).  Download program  View Presentation with slides  

Janssen RPA
The Unconventional ACL Meeting...The Sequel
Anatomic medial reconstruction of the knee

Anatomic medial reconstruction of the knee

RPA Janssen will present the lecture: Anatomic medial reconstruction of the knee at the inaugural NVA-Advanced Arthroscopy Course Knee of the Dutch Arthroscopy Society (November 4, 2013, Erasmus University, Rotterdam, The Netherlands.

Janssen RPA
NVA Advanced Knee Course 2013
Anterior cruciate ligament reconstruction with hamstring tendons and accelerated rehabilitation: a 10-year prospective study on clinical results, knee osteoarthritis and its predictors

Anterior cruciate ligament reconstruction with hamstring tendons and accelerated rehabilitation: a 10-year prospective study on clinical results, knee osteoarthritis and its predictors

RPA Janssen, M.D. has been invited to present his scientific work on long term results after ACL reconstructions at the 30th AGA Jubilee Congress. As President, he will also represent the Dutch Arthroscopy Society (NVA) at the meeting with a delegation of...

Janssen RPA, Du Mée AWF, Valkenburg v J, Sala HAGM, Tseng CM

Current scientific research

Culturing human osteoarthritic osteochondral explants

Culturing human osteoarthritic osteochondral explants

Current knee osteoarthritis (OA) treatments are sub-optimal and not long-lasting. Within the osteoarthritis moonshot, osteochondral implants for focal cartilage defects are developed which need to regenerate cartilage and bone and integrate with the adjacent tissues....

Meike W.A. Kleuskens, (René) C.C. van Donkelaar, Rob P.A. Janssen and Keita Ito
Pediatric ACL reconstruction

Pediatric ACL reconstruction

RPA Janssen MD PhD coordinates several research projects (Msc and PhD_ on pediatric ACL reconstructions with open physis. Cooperation with ESSKA, University Aarhus (Denmark), Dutch Arthroscopy Society (NVA) and Maastricht University.

Janssen RPA, Reijman M, Faunø P, Rhijn van LW, Dietvorst M
Biology and remodelling of cruciate ligaments in humans. Master and Phd projects with Eindhoven University of Technology Eindhoven

Biology and remodelling of cruciate ligaments in humans. Master and Phd projects with Eindhoven University of Technology Eindhoven

The research group of the Orthopaedic Associates Eindhoven Greater Area led by RPA Janssen MD PhD and M. Reijman PhD has started new cruciate ligament research projects in association with CC van Donkelaar PhD and J Foolen PhD of the faculty Biomedical...

Groningen van B, Stefanoska D, Vijven van M, Laar van de Esmay, Ijzendoorn van L, Lopata R, Boer de J, Ito K, Foolen J, Donkelaar van CC, Steen van der MC, Janssen RPA
STARR-Trial Meniscus

STARR-Trial Meniscus

Máxima Medical Center is one of the three centers in the new multicenter randomised controlled trial for best treatment of acute meniscal injuries: the STARR-Trial.  More information on STARR-Trial (Dutch)

Eijgenraam S, Janssen RPA, Reyman M et al.
Validation of a new extension knee program in knee osteoarthritis

Validation of a new extension knee program in knee osteoarthritis

Pilot study for validation of a new knee extension program for patients with gait pattern disorders in knee osteoarthritis. The study is performed in cooperation with Erasmus University Rotterdam and Maastricht University, The Netherlands. 

Tolk J, Brooymans FAM, Janssen RPA, Bierma-Zeinstra SMA

Awards

Editor’s Pick Prof Stafano Zaffagnini Journal of Experimental Orthopaedics

Editor’s Pick Prof Stafano Zaffagnini Journal of Experimental Orthopaedics

Dietvorst, M., Verhagen, S., van der Steen, M. C., van Douveren, F. Q. M. P., & Janssen, R. P. A. (2024). Anterolateral augmentation procedures during anterior cruciate ligament reconstructions in skeletally immature patients: Scoping review of surgical techniques and outcomes.
Journal of Experimental Orthopaedics, 2024:11(1), Article e12012. https://doi.org/10.1002/jeo2.12012
Bsc thesis. Conceptual database design of the ACL patient’s data

Bsc thesis. Conceptual database design of the ACL patient’s data

The Thesis explores the topic of database design, and its first couple of stages. Going from ana- lyzing the organizational structure of the hospital, and analyzing the data that is collected during a patient’s treatment process, to establishing a concrete...

Jovan Sakovic
Innovation Space Bachelor End Project - BSc Data Science Thesis (June 2021)

PhD-MSc-BSc Thesis Knee

Bsc thesis. Conceptual database design of the ACL patient’s data

Bsc thesis. Conceptual database design of the ACL patient’s data

The Thesis explores the topic of database design, and its first couple of stages. Going from ana- lyzing the organizational structure of the hospital, and analyzing the data that is collected during a patient’s treatment process, to establishing a concrete...

Jovan Sakovic
Innovation Space Bachelor End Project - BSc Data Science Thesis (June 2021)

Phd-MSc-BSc Thesis Value-Based Health Care

Good Clinical Practice

Diploma Radiation Protection level 4A/M (Dutch)

Diploma Radiation Protection level 4A/M (Dutch)

RPA Janssen MD PhD has been awarded the diploma Radiation Protection Level 4A/M for Medical Specialists after succesfully passing the national board examination on November 4, 2015. 

Janssen RPA
Diploma Good Clinical Practice

Diploma Good Clinical Practice

RPA Janssen MD PhD has been awarded the diploma Good Clinical Practice after succesfully passing the national board examination on November 17th, 2011. The diploma is a prerequisite for conducting human scientific research in Europe.  On Mach 15 2017,...

Janssen RPA